产品货号：
Z34733
中文名称：
MCM7抗体
英文名称：
Anti-MCM7 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MCM7 Antibody |
| 指标别名 | CDABP0042;CDC47;CDC47 homolog;MCM2;MCM7;P1.1 MCM3;P1CDC47;P85MCM;PNAS 146 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | MCM7 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human MCM7 Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. |
| 实际分子量 | 81KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MCM7(Minichromosome Maintenance,s.Cerevisiae,homolog of,7),also called CDC47,FORMERLY,is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication.The MCM7 gene is mapped to 7q22.1.MCM7 plays a pivotal role in the G1/S phase transition,orchestrating the correct assembly of replication forks on chromosomal DNA and ensuring that all the genome is replicated once and not more than once at each cell cycle.The MCM7 gene contains 15 exons.The miRNAs MIR106B,MIR93,and MIR25 are clustered in a 5-prime to 3-prime orientation within intron 13.It has been found that MCM7 and the precursors of microRNAs (miRNAs) MIR106B,MIR93,and MIR25,all of which arise from intron 13 of the MCM7 gene,were overexpressed with almost perfect correlation in 5 of 10 human gastric tumors. |
| Uniprot ID | P33993 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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